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Forschung 5: Molekularbiologie des Humanparasiten Schistosoma

Artikel in Zeitschriften:

Kunz,W., Opatz,K., Finken,M., and Symmons,P. (1987). Sequences of two genomic fragments containing an identical coding region for a putative eggshell precursor protein of Schistosoma mansoni. Nucleic Acids Res. 15, 5894.

Kunz,W. and Symmons,P. (1987). Gender-specifically expressed genes in Schistosoma mansoni. Acta Trop. (Basel) 44, 90-93.

Meusel,G., Symmons,P., and Kunz,W. (1987). Two gender-specific transcripts predominate in the mRNA of adult female Schistosoma mansoni. J. Parasit. 73, 436-437.

Köster,B., Dargatz,H., Schröder,J., Hirzmann,J., Haarmann,C., Symmons,P., and Kunz,W. (1988). Identification and localisation of the products of a putative eggshell precursor gene in the vitellarium of Schistosoma mansoni. Mol. Biochem. Parasitol. 31, 183-198.

Schröder,J., Symmons,P., and Kunz,W. (1989). Immunenzymatische Farbkodierung zur Erkennung von DNA-Klonen in Expressionsvektor-Bibliotheken. BioEng. 5, 24-30.

West,S., Schröder,J., and Kunz,W. (1990). A multiple-staining procedure for the detection of different DNA fragments on a single blot. Anal. Biochem. 190, 254-258.

Schröder,J. and Kunz,W. (1991). Monospezifische Antikörper: Affinitätsreinigung mit Hilfe Filter-gebundener Antigene. Bioforum  14, 235-239.

Dietzel,J., Hirzmann,J., Preis,D., Symmons,P., and Kunz,W. (1992). Ferritins of Schistosoma mansoni:  Sequence comparison and expression in female and male worms. Mol. Biochem. Parasitol. 50, 245-254.

Höltke,H.J., Ettl,I., Finken,M., West,S., and Kunz,W. (1992). Multiple nucleic acid labeling and rainbow detection. Anal. Biochem. 207, 24-31.

Maniak,M., Schmitz,J., and Kunz,W. (1992). Studies on immunodominant antigens and muscle proteins in Schistosoma mansoni. J. Cell. Biochem. 16A, 149.

Weston,D., Schmitz,J., Kemp,W.M., and Kunz,W. (1993). Cloning and sequence of a complete myosin heavy chain cDNA from Schistosoma mansoni. Mol. Biochem. Parasitol. 58, 161-164.

Finken,M., Sobek,A., Symmons,P., and Kunz,W. (1994). Characterization of the complete protein disulfide isomerase gene of Schistosoma mansoni and identification of the tissues of its expression. Mol. Biochem. Parasitol. 64, 135-144.

Kunz,W., Grevelding,C.G., and Gohr,L. (1994). Schistosome research newsgroup. Parasitol. Today 10, 250.

Kunz,W., Grevelding,C.G., and Gohr,L. (1994). Schistosome research newsgroup update. Parasitol. Today 10, 445.

Bodor,O., Schmidt,J., and Kunz,W. (1995). Localization of paramyosin in S.mansoni. Zbl. Bakt. 182, 130-131.

Butler,R., Michel,A., Kunz,W., and Klinkert,M.-Q. (1995). Sequence of Schistosoma mansoni cathepsin C and its structural comparison with papain and cathepsins B and L of the parasite. Protein and Peptide Letters 2, 313-320.

Gohr,L., Maniak,M., and Kunz,W. (1995). Paramyosin of Schistosoma mansoni: multifunctionality and host-parasite interaction. Zbl. Bakt.  282, 148.

Kunz,W., Gohr,L., Grevelding,C.G., Schüßler,P., Sommer,G., Menrath,M., and Michel,A. (1995). Schistosoma mansoni: Control of female fertility by the male. Mem. Inst. Oswaldo Cruz 90, 185-189.

Kunz,W., Grevelding,C.G., and Gohr,L. (1995). Schistosome Research Newsgroup. Parasitol. Res. 81, A3.

Kunz,W., Grevelding,C.G., and Gohr,L. (1995). Schistosome research newsgroup. Parasitol. Today 11, 356.

Menrath,M., Michel,A., and Kunz,W. (1995). A female-specific sequence of Schistosoma mansoni encoding a mucin-like protein that is expressed in the epithelial cells of the reproductive duct. Parasitology 111, 477-483.

Michel,A., Ghoneim,H., Resto,M., Klinkert,M.-Q., and Kunz,W. (1995). Sequence, characterization and localization of a cysteine proteinase cathepsin L in Schistosoma mansoni. Mol. Biochem. Parasitol. 73, 7-18.

Schüßler,P., Pötters,E., Winnen,R., Bottke,W., and Kunz,W. (1995). An isoform of ferritin as a component of protein yolk platelets in Schistosoma mansoni. Mol. Reprod. Dev. 41, 325-330.

Schüßler,P., Gohr,L., Sommer,G., Kunz,W., and Grevelding,C.G. (1995). Combined isolation of nucleic acids and protein from small amounts of tissue. Trends Genet. 11, 378-379.

Winnen, R., Schüßler, P., Sommer, G., Bottke, W., Grevelding, C. G., and Kunz, W. Fer 1 is a female-preferentially and developmentally expressed component of protein yolk in Schistosoma mansoni. Journal of Biological Chemistry-Hoppe-Seyler 376, 169. 1995.
Grevelding,C.G., Kampkötter,A., Hollmann,M., Schäfer,U., and Kunz,W. (1996). Direct PCR on fruitflies and blood flukes without prior DNA isolation. Nucleic Acids Res. 24, 4100-4101.

Grevelding,C.G., Kampkötter,A., Gohr,L., Tanaka,M., Opatz,K., Quack,T., and Kunz,W. (1996). Genome instability in Schistosoma mansoni. Tropical Medicine and International Health I, A8.

Klinkert,M.-Q. and Kunz,W. (1996). Digestion of haemoglobin by schistosomes. Parasitol. Today 12, 165.

Kunz,W. (1996). Surfing the internet: World Wide Web resources for parasitologists. Parasitol. Res. 82, A4.

Schmidt,J., Bodor,O., Gohr,L., and Kunz,W. (1996). Paramyosin isoforms of Schistosoma mansoni are phosphorylated and localized in a large variety of muscle types. Parasitology 112, 459-467.

Schüßler,P., Grevelding,C.G., and Kunz,W. (1996). More WWW addresses for parasitologists. Parasitol. Today 12, 291.

Schüßler,P., Pötters,E., Winnen,R., Michel,A., Bottke,W., and Kunz,W. (1996). Ferritin mRNAs in Schistosoma mansoni do not have iron-responsive elements for post-transcriptional regulation. Eur. J. Biochem. 241, 64-69.

Finken-Eigen,M. and Kunz,W. (1997). Schistosoma mansoni: Gene structure and localization of a homologue to cysteine protease ER 60. Exp. Parasitol. 86, 1-7.

Grevelding,C.G., Sommer,G., and Kunz,W. (1997). Female-specific gene expression in Schistosoma mansoni is regulated by pairing. Parasitology 115, 635-640.

Grevelding,C.G., Kampkötter,A., and Kunz,W. (1997). Schistosoma mansoni: Sexing cercariae by PCR without DNA extraction. Exp. Parasitol. 85, 99-100.

Schüßler,P., Grevelding,C.G., and Kunz,W. (1997). Identification of Ras, MAP kinases, and a GAP protein in Schistosoma mansoni by immunoblotting and their putative involvement in male-female interaction. Parasitology 115, 629-634.

Schüßler,P., Grevelding,C.G., and Kunz,W. (1997). Cloning and characterization of elongation factor 1- a of Schistosoma mansoni. Parasitol. Res. 83, 206-208.

Quack,T., Doenhoff,M.J., Kunz,W., and Grevelding,C.G. (1998). Schistosoma mansoni: The varying occurrence of repetitive elements in different strains shows sex-specific polymorphisms. Exp. Parasitol. 89, 222-227.

Schüßler,P., Köhrer,K., Finken-Eigen,M., Michel,A., Grevelding,C.G., and Kunz,W. (1998). A female-specific cDNA sequence of Schistosoma mansoni encoding an amidase that is expressed in the gastrodermis. Parasitology 116, 131-137.

Kampkötter,A., Ridgers,I., Johnston,D.A., Rollinson,D., Kunz,W., and Grevelding,C.G. (1999). Schistosoma mansoni: Cloning and characterization of the ras-homologue. Exp. Parasitol. 91, 280-283.

Kapp,K., Schüßler,P., Kunz,W., and Grevelding,C.G. (2001). Identification, isolation and characterisation of a Fyn-like tyrosine kinase from Schistosoma mansoni. Parasitology 122, 317-327.

Kunz,W. (2001). Schistosome male–female interaction: induction of germ-cell differentiation. Trends Parasitol. 17, 227-231.

Schechtman,D., Winnen,R., Tarrab-Hazdai,R., Ram,D., Shinder,V., Grevelding,C.G., Kunz,W., and Arnon,R. (2001). Expression and immunolocalization of the 14-3-3 protein of Schistosoma mansoni. Parasitology 123, 573-582.

Knobloch,J., Winnen,R., Quack,M., Kunz,W., and Grevelding,C.G. (2002). A novel Syk-family tyrosine kinase from Schistosoma mansoni which is preferentially transcribed in reproductive organs. Gene 294, 87-97.

Knobloch,J., Kunz,W., and Grevelding,C.G. (2002). Quantification of DNA synthesis in multicellular organisms by a combined DAPI and BrdU technique. Dev. Growth Diff. 44, 559-563.

Wippersteg,V., Kapp,K., Kunz,W., and Grevelding,C.G. (2002). Characterisation of the cysteine protease ER60 in transgenic Schistosoma mansoni larvae. Int. J. Parasitol. 32, 1219-1224.

Wippersteg,V., Kapp,K., Kunz,W., and Grevelding,C.G. (2002). Biolistic gene transfer to generate transgenic schistosomes. Bio-Rad tech note 2768, 1-4.

Wippersteg,V., Kapp,K., Kunz,W., Jackstadt,P., Zahner,H., and Grevelding,C.G. (2002). HSP70-controlled GFP expression in transiently transformed schistosomes. Mol. Biochem. Parasitol. 120, 141-150.

Kapp,K., Coustau,C., Wippersteg,V., Jourdane,J., Kunz,W., and Grevelding,C.G. (2003). Transplantation of in vitro-generated Schistosoma mansoni mother sporocysts into Biomphalaria glabrata. Parasitol. Res. 91, 482-485.

Michel,A., Knobloch,J., and Kunz,W. (2003). P 19: a female and tissue specifically expressed gene in Schistosoma mansoni, regulated by pairing with the male. Parasitology 127, 519-524.

Kapp,K., Knobloch,J., Schüßler,P., Sroka,S., Lammers,R., Kunz,W., and Grevelding,C.G. (2004). The Schistosoma mansoni Src kinase TK3 is expressed in the gonads and likely involved in cytoskeletal organization. Mol. Biochem. Parasitol. 138, 171-182.

Ebersberger,I., Knobloch,J., and Kunz,W. (2005). Cracks in the shell-zooming in on eggshell formation in the human parasite Schistosoma mansoni. Dev. Genes Evol. 215, 261-267.

Knobloch,J., Kunz,W., and Grevelding,C.G. (2006). Herbimycin A suppresses mitotic activity and egg production of female Schistosoma mansoni. Int. J. Parasitol. 36, 1261-1272.



Kunz,W. (1988). Genetics of parasites. In Parasitology in focus: facts and trends, H.Mehlhorn, ed. (Berlin: Springer-Verlag), pp. 368-390.

Kunz,W. and West,S. (1992). Azo dyes. In Nonradioactive labeling and detection of biomolecules, C.Kessler, ed. (Berlin: Springer-Verlag), pp. 161-164.

Schüßler,P., Grevelding,C.G., and Kunz,W. (2000). Azo dyes. In Nonradioactive analysis of biomolecules, C.Kessler, ed. (Berlin: Springer-Verlag), pp. 253-257.

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